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About this MedsFacts analysis covering adverse side effect reports of EXEMESTANE patients who developed MUSCLE SPASMS.

MedsFacts provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and MedsFacts user submissions. Between January 2004 and October 2012, 11 individuals taking EXEMESTANE reported MUSCLE SPASMS to the FDA. A total of 1162 EXEMESTANE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between EXEMESTANE and MUSCLE SPASMS. In doing so, we compare EXEMESTANE with other drugs that cause MUSCLE SPASMS, to help you evaluate whether or not EXEMESTANE causes MUSCLE SPASMS. Likewise, this page shows the most highly-reported side effects of EXEMESTANE, so you can see if MUSCLE SPASMS ranks among EXEMESTANE's most well-known side effects.
Summary Statistics
Reports of EXEMESTANE causing MUSCLE SPASMS: 11
Reports of any side effect of EXEMESTANE : 1162
Percentage of EXEMESTANE patients where MUSCLE SPASMS is a reported side effect: 0.9466%

FDA reports of any drug causing MUSCLE SPASMS : 43893
Average percentage for all medicated patients where MUSCLE SPASMS is reported as a complication: 0.2751%

Physician opinion on EXEMESTANE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing EXEMESTANE:
BREAST CANCER ( 630 patients )
BREAST CANCER METASTATIC ( 64 patients )
BREAST CANCER FEMALE ( 45 patients )
DRUG USE FOR UNKNOWN INDICATION ( 12 patients )
NEOPLASM MALIGNANT ( 7 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 6 patients )
HORMONE THERAPY ( 6 patients )
ADJUVANT THERAPY ( 5 patients )
HORMONE SUPPRESSION THERAPY ( 5 patients )
METASTASES TO BONE ( 4 patients )
BREAST CANCER STAGE III ( 4 patients )
ANTIOESTROGEN THERAPY ( 3 patients )
OVARIAN DISORDER ( 3 patients )
BREAST CANCER RECURRENT ( 3 patients )
BREAST NEOPLASM ( 3 patients )
PROPHYLAXIS ( 2 patients )
HORMONE LEVEL ABNORMAL ( 2 patients )
OVARIAN FAILURE ( 2 patients )
PROPHYLACTIC CHEMOTHERAPY ( 2 patients )
CHEMOTHERAPY ( 2 patients )
HYPERTENSION ( 1 patients )
BLOOD OESTROGEN DECREASED ( 1 patients )
NEOPLASM PROPHYLAXIS ( 1 patients )
ILL-DEFINED DISORDER ( 1 patients )
AROMATASE INHIBITION THERAPY ( 1 patients )
OOPHORECTOMY ( 1 patients )
THERAPEUTIC PROCEDURE ( 1 patients )
ENDOMETRIOSIS ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with MUSCLE SPASMS:

FORTEO (4380 patients)
FOSAMAX (4274 patients)
LIPITOR (3384 patients)
ASPIRIN (3280 patients)
AVONEX (2583 patients)
TYSABRI (2520 patients)
VIOXX (2377 patients)
CRESTOR (2007 patients)
SYNTHROID (1703 patients)
NEXIUM (1569 patients)
SEROQUEL (1534 patients)
NEURONTIN (1504 patients)
LISINOPRIL (1488 patients)
LYRICA (1487 patients)
HUMIRA (1429 patients)
XANAX (1311 patients)
ZOCOR (1231 patients)
ATENOLOL (1173 patients)
VITAMIN D (1148 patients)
CYMBALTA (1111 patients)
LASIX (1110 patients)
SIMVASTATIN (1094 patients)
ZOMETA (1066 patients)
PRILOSEC (1065 patients)
OMEPRAZOLE (1063 patients)
HEPARIN SODIUM INJECTION (1058 patients)
HYDROCHLOROTHIAZIDE (1055 patients)
PREDNISONE (1049 patients)
CELEBREX (1001 patients)
ENBREL (1000 patients)
PLAVIX (998 patients)
ZOLOFT (988 patients)
COUMADIN (967 patients)
AMBIEN (943 patients)
CHANTIX (923 patients)
ALBUTEROL (919 patients)
CALCIUM (903 patients)
OXYCONTIN (894 patients)
LEVOTHYROXINE SODIUM (879 patients)
BACLOFEN (828 patients)
FUROSEMIDE (822 patients)
GLEEVEC (822 patients)
NORVASC (821 patients)
PAXIL (809 patients)
IBUPROFEN (809 patients)
GABAPENTIN (802 patients)
REBIF (787 patients)
DURAGESIC-100 (783 patients)
REVLIMID (782 patients)
TOPROL-XL (780 patients)
ADVAIR DISKUS 100/50 (777 patients)
PREVACID (770 patients)
AREDIA (767 patients)
VICODIN (762 patients)
LEXAPRO (755 patients)
PREMARIN (752 patients)
MIRENA (749 patients)
EFFEXOR (735 patients)
PROTONIX (731 patients)
SINGULAIR (711 patients)
FOLIC ACID (708 patients)
REMICADE (706 patients)
PERCOCET (700 patients)
DIOVAN (696 patients)
METFORMIN HCL (695 patients)
LEVAQUIN (684 patients)
NIASPAN (673 patients)
ATIVAN (669 patients)
ACETAMINOPHEN (643 patients)
METHOTREXATE (641 patients)
FLEXERIL (640 patients)
LORAZEPAM (639 patients)
CLONAZEPAM (635 patients)
VALIUM (623 patients)
PROZAC (619 patients)
KLONOPIN (613 patients)
LANTUS (585 patients)
POTASSIUM CHLORIDE (578 patients)
ZETIA (570 patients)
LORTAB (559 patients)
OXYCODONE HCL (559 patients)
SANDOSTATIN LAR (553 patients)
SPIRIVA (552 patients)
BYETTA (550 patients)
METOPROLOL TARTRATE (537 patients)
BONIVA (537 patients)
FISH OIL (532 patients)
DIAZEPAM (527 patients)
ALENDRONATE SODIUM (525 patients)
BETASERON (515 patients)
ZYRTEC (499 patients)
CELEXA (499 patients)
MULTI-VITAMIN (497 patients)
WELLBUTRIN (490 patients)
MULTI-VITAMINS (488 patients)
LIORESAL (485 patients)
ALLOPURINOL (475 patients)
TRAZODONE HCL (467 patients)
ALPRAZOLAM (466 patients)
ASCORBIC ACID (464 patients)
TRAMADOL HCL (463 patients)
AMLODIPINE (457 patients)
YAZ (451 patients)
DIGOXIN (447 patients)
PREDNISONE TAB (436 patients)
DEXAMETHASONE (434 patients)
BENADRYL (433 patients)
FOSAMAX PLUS D (433 patients)
ZANTAC (431 patients)
ALLI (430 patients)
ACTONEL (427 patients)
SOMA (422 patients)
ALLEGRA (416 patients)
AMITRIPTYLINE HCL (413 patients)
TRICOR (409 patients)
WARFARIN SODIUM (408 patients)
EFFEXOR XR (394 patients)
CALCIUM CARBONATE (392 patients)
VITAMIN E (389 patients)
FENTANYL (389 patients)
EVISTA (387 patients)
VITAMIN B-12 (387 patients)
MORPHINE (386 patients)
LEVOXYL (374 patients)
GLUCOPHAGE (368 patients)
RISPERDAL (364 patients)
NITROGLYCERIN (364 patients)
METOPROLOL (364 patients)
COZAAR (364 patients)
YASMIN (363 patients)
ZYPREXA (361 patients)
VYTORIN (361 patients)
TOPAMAX (360 patients)
SYMBICORT (359 patients)
CLONIDINE (358 patients)
ACCUTANE (355 patients)
COREG (341 patients)
RECLAST (339 patients)
RANITIDINE (339 patients)
ACTOS (339 patients)
FLONASE (338 patients)
DECADRON (338 patients)
SKELAXIN (336 patients)
ELAVIL (335 patients)
ARIMIDEX (334 patients)
AMOXICILLIN (332 patients)
INSULIN (331 patients)
NUVARING (330 patients)
IRON (329 patients)
SIMCOR (327 patients)
TYLENOL (324 patients)
LAMICTAL (322 patients)
AVANDIA (322 patients)
ABILIFY (319 patients)
TYLENOL (CAPLET) (319 patients)
ULTRAM (318 patients)
RAMIPRIL (316 patients)
ZOFRAN (314 patients)
POTASSIUM (309 patients)
CIPROFLOXACIN (308 patients)
NEXAVAR (308 patients)
METFORMIN (306 patients)
PANTOPRAZOLE (303 patients)
ZITHROMAX (303 patients)
ZANAFLEX (301 patients)
RIBAVIRIN (301 patients)
AVELOX (299 patients)
HUMALOG (297 patients)
CLARITIN (296 patients)
NAPROXEN (292 patients)
ALTACE (289 patients)
PRAVACHOL (289 patients)
DILAUDID (289 patients)
COLACE (287 patients)
CALCIUM (UNSPECIFIED) (286 patients)
RISPERDAL CONSTA (285 patients)
PREMPRO (284 patients)
MOTRIN (283 patients)
DOXYCYCLINE (282 patients)
SPIRONOLACTONE (277 patients)
PROMETHAZINE (276 patients)
HYDROCODONE (273 patients)
GLIPIZIDE (272 patients)
PAROXETINE HCL (270 patients)
LOPRESSOR (269 patients)
HYDROCODONE BITARTRATE (267 patients)
FLOMAX (267 patients)
PEPCID (266 patients)
VERAPAMIL (266 patients)
GLYBURIDE (265 patients)
VITAMINS (264 patients)
BOTOX (262 patients)
REQUIP (262 patients)
REGLAN (262 patients)
PEGASYS (261 patients)
PRAVASTATIN (255 patients)
LOVENOX (253 patients)
MOBIC (251 patients)
CIPRO (249 patients)
MODOPAR (247 patients)
LOVASTATIN (247 patients)
ACYCLOVIR (246 patients)
XOLAIR (246 patients)
FEMARA (245 patients)
ATORVASTATIN CALCIUM (245 patients)
CITALOPRAM HYDROBROMIDE (244 patients)
METOCLOPRAMIDE (244 patients)
TEMAZEPAM (244 patients)
ACIPHEX (243 patients)
MIRALAX (243 patients)
Most common side effects for patients taking EXEMESTANE:
ARTHRALGIA (96 patients)
OSTEONECROSIS (80 patients)
PULMONARY EMBOLISM (75 patients)
PAIN (73 patients)
PAIN IN EXTREMITY (67 patients)
NAUSEA (67 patients)
METASTASES TO BONE (62 patients)
FALL (59 patients)
FATIGUE (58 patients)
OSTEONECROSIS OF JAW (57 patients)
ANXIETY (56 patients)
HOT FLUSH (55 patients)
ASTHENIA (55 patients)
BONE DISORDER (55 patients)
DIZZINESS (53 patients)
DEATH (50 patients)
VOMITING (50 patients)
TOOTH EXTRACTION (47 patients)
OSTEOMYELITIS (47 patients)
BONE PAIN (46 patients)
DYSPNOEA (44 patients)
BACK PAIN (44 patients)
DIARRHOEA (44 patients)
METASTASES TO LIVER (43 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (42 patients)
PARAESTHESIA (39 patients)
DEEP VEIN THROMBOSIS (39 patients)
HEADACHE (38 patients)
OSTEOPENIA (38 patients)
MALAISE (37 patients)
PAIN IN JAW (36 patients)
CHEST PAIN (36 patients)
DEPRESSION (34 patients)
ANAEMIA (33 patients)
ABDOMINAL PAIN (32 patients)
VERTIGO (32 patients)
IMPAIRED HEALING (32 patients)
WEIGHT DECREASED (31 patients)
DIABETES MELLITUS (31 patients)
URINARY TRACT INFECTION (31 patients)
DECREASED INTEREST (31 patients)
PATHOLOGICAL FRACTURE (30 patients)
BONE LESION (30 patients)
CEREBROVASCULAR ACCIDENT (30 patients)
ATRIAL FIBRILLATION (28 patients)
INTERVERTEBRAL DISC DEGENERATION (28 patients)
PYREXIA (27 patients)
HYPERTENSION (27 patients)
CONDITION AGGRAVATED (26 patients)
CONFUSIONAL STATE (26 patients)
HEPATIC FAILURE (26 patients)
COUGH (26 patients)
NEUTROPENIA (25 patients)
OEDEMA PERIPHERAL (25 patients)
MALIGNANT NEOPLASM PROGRESSION (25 patients)
CATARACT (25 patients)
NEOPLASM MALIGNANT (25 patients)
DRUG INTERACTION (24 patients)
DECREASED APPETITE (24 patients)
HYPOAESTHESIA (24 patients)
ROTATOR CUFF SYNDROME (24 patients)
NECK PAIN (23 patients)
INSOMNIA (22 patients)
HYPERCHOLESTEROLAEMIA (22 patients)
LYMPHADENOPATHY (22 patients)
MOUTH ULCERATION (22 patients)
NEUROPATHY PERIPHERAL (22 patients)
SYNCOPE (22 patients)
ERYTHEMA (22 patients)
HEPATIC LESION (22 patients)
HYPONATRAEMIA (21 patients)
THROMBOCYTOPENIA (20 patients)
MUSCULOSKELETAL DISORDER (20 patients)
PELVIC PAIN (19 patients)
SPINAL OSTEOARTHRITIS (19 patients)
HYPOTENSION (19 patients)
PLEURAL EFFUSION (19 patients)
RASH (19 patients)
MYALGIA (19 patients)
ABDOMINAL DISTENSION (18 patients)
ACTINOMYCOSIS (18 patients)
SWELLING (18 patients)
CHILLS (18 patients)
MUSCULAR WEAKNESS (17 patients)
ABSCESS JAW (17 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (17 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (17 patients)
INJURY (17 patients)
METASTASES TO SPINE (17 patients)
NIGHT SWEATS (17 patients)
INFLUENZA LIKE ILLNESS (17 patients)
DEHYDRATION (17 patients)
MASS (17 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (17 patients)
CELLULITIS (17 patients)
TOOTH FRACTURE (17 patients)
RENAL FAILURE (16 patients)
ALOPECIA (16 patients)
HAEMOGLOBIN DECREASED (16 patients)
LOSS OF CONSCIOUSNESS (16 patients)
BREAST CANCER (16 patients)
BREAST CANCER METASTATIC (16 patients)
GRANULOMA (16 patients)
BURSITIS (16 patients)
CARPAL TUNNEL SYNDROME (16 patients)
TRANSIENT ISCHAEMIC ATTACK (15 patients)
ARTHRITIS (15 patients)
BALANCE DISORDER (15 patients)
SINUSITIS (15 patients)
GAIT DISTURBANCE (15 patients)
STRESS FRACTURE (15 patients)
FEMUR FRACTURE (15 patients)
PLATELET COUNT INCREASED (15 patients)
MUSCULOSKELETAL PAIN (15 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (15 patients)
HYDRONEPHROSIS (15 patients)
COMPRESSION FRACTURE (15 patients)
PERIODONTAL DISEASE (14 patients)
ANHEDONIA (14 patients)
GINGIVAL SWELLING (14 patients)
SENSORY LOSS (14 patients)
NEPHROLITHIASIS (14 patients)
PSORIASIS (14 patients)
PUBIS FRACTURE (14 patients)
ABSCESS ORAL (13 patients)
FEBRILE NEUTROPENIA (13 patients)
FLANK PAIN (13 patients)
LUNG DISORDER (13 patients)
OSTEOARTHRITIS (13 patients)
OVARIAN CYST (13 patients)
LUMBAR SPINAL STENOSIS (13 patients)
HYPERHIDROSIS (13 patients)
STAPHYLOCOCCAL INFECTION (13 patients)
WOUND DEBRIDEMENT (13 patients)
SURGERY (13 patients)
RENAL FAILURE ACUTE (13 patients)
RADIUS FRACTURE (13 patients)
RADICULOPATHY (13 patients)
TOOTH DISORDER (13 patients)
SYNOVIAL CYST (13 patients)
TENDONITIS (12 patients)
OBESITY (12 patients)
ABDOMINAL PAIN LOWER (12 patients)
KLEBSIELLA SEPSIS (12 patients)
HEPATIC CIRRHOSIS (12 patients)
HERNIAL EVENTRATION (12 patients)
MENISCUS LESION (12 patients)
PERIOSTITIS (12 patients)
AGEUSIA (12 patients)
LUMBAR RADICULOPATHY (12 patients)
PURULENT DISCHARGE (12 patients)
FEELING ABNORMAL (12 patients)
AORTIC ARTERIOSCLEROSIS (12 patients)
FRACTURE (12 patients)
APHASIA (12 patients)
URETHRAL CARUNCLE (12 patients)
EAR INFECTION (12 patients)
PELVIC HAEMATOMA (12 patients)
WOUND DEHISCENCE (12 patients)
CYSTITIS HAEMORRHAGIC (12 patients)
MEMORY IMPAIRMENT (12 patients)
OSTEOSCLEROSIS (12 patients)
BLADDER DISORDER (12 patients)
SINUS BRADYCARDIA (12 patients)
SKIN NECROSIS (12 patients)
DYSPHAGIA (12 patients)
NEURALGIA (12 patients)
JAW FRACTURE (12 patients)
PERIARTHRITIS (12 patients)
BONE NEOPLASM (12 patients)
CONTUSION (12 patients)
EPISTAXIS (12 patients)
ESCHERICHIA INFECTION (12 patients)
CYST (12 patients)
CYSTITIS KLEBSIELLA (12 patients)
CANDIDIASIS (12 patients)
LYMPHADENOPATHY MEDIASTINAL (12 patients)
CARDIAC MURMUR (12 patients)
DENTAL FISTULA (12 patients)
HEPATIC FUNCTION ABNORMAL (12 patients)
CENTRAL VENOUS CATHETERISATION (12 patients)
PALPITATIONS (12 patients)
CEREBRAL HAEMORRHAGE (12 patients)
HERPES ZOSTER (12 patients)
CHOLELITHIASIS (12 patients)
PATELLA FRACTURE (12 patients)
DISEASE PROGRESSION (12 patients)
FRACTURED SACRUM (12 patients)
JOINT SWELLING (11 patients)
POST HERPETIC NEURALGIA (11 patients)
DRY MOUTH (11 patients)
DYSGEUSIA (11 patients)
PHLEBITIS (11 patients)
THROMBOSIS (11 patients)
MUSCLE SPASMS (11 patients)
PRIMARY SEQUESTRUM (11 patients)
BLISTER (11 patients)
DIPLOPIA (11 patients)
NEOPLASM PROGRESSION (11 patients)
MENOPAUSE (11 patients)
BLOOD PRESSURE INCREASED (11 patients)
CARDIAC FAILURE CONGESTIVE (11 patients)
CAROTID BRUIT (11 patients)
CEREBRAL ATROPHY (11 patients)
SCIATICA (11 patients)
PANCREATIC ATROPHY (11 patients)
CERVICAL SPINAL STENOSIS (11 patients)
CHEST DISCOMFORT (11 patients)
HYPERCALCAEMIA (11 patients)
NEURITIS (11 patients)

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